EXPLAINER: Lab results and their interpretation

Dear @hopefulone,

There is no real difference in your DNA levels (if stays within 2-fold of the previous reading, you should probably interpret it as stable).

Regarding your other results:

  • Genotype reflects where the virus is geographically from, and may predict your responses to certain treatments, or progression of liver disease. Usually though, it doesn’t affect your clinical treatment very much. See here: Living with cirrhosis - #4 by ThomasTu
  • Basal core or pre-core mutations are similar, the presence of these variations in the virus are linked to different outcomes, but I’m not sure the science is really settled on this. Good to know just in case future work shows that they are really important.
  • Yes, HBeAb becomes positive when HBeAg goes negative in a chronic HBV infection. The flag says abnormal because in people without HBV infection HBeAg is negative.
  • Inactive HBsAG Carrier sounds like a reasonable interpretation of your results

Generally, part of the ongoing monitoring, you’ll be getting the HBV-specific tests (HBeAg, Anti-HBe, HBsAg, Anti-HBs, HBV DNA) and ultrasounds as you have talked about. You’d also be getting liver function tests (a panel of blood tests).

Hope this helps,
Thomas

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