Hi @PuallyHBV,
Virus genotype and how it affects disease progression is something that is still under research. I’ve attached below a table of different outcomes that are associated with each genotype (from the paper I coauthored here: https://www.nature.com/articles/s41575-020-0296-6). We don’t really know what drives these differences (whether it’s the patient themselves, the virus, or a combination of the two), but it’s still a matter of research.
Hope this helps,
Thomas