Metformin why not?

[ThomasTu]

Dear @catcher.007,

As mentioned previously (for anyone who had not seen the old posts), there doesn’t seem to be any benefits to taking metformin in clinical trials investigating this. Links here:

Upcoming HBV treatments

Dear @OlgaP, I had not actually heard of using metformin as an anti-HBV drug, so I did a little bit of research. Looks like there is an interesting study showing that metformin does decrease HBsAg, HBeAg and HBV DNA levels in a petri dish: https://onlinelibrary.wiley.com/doi/abs/10.1111/jvh.12187. I think this has justified a clinical trial that is ongoing in China: https://clinicaltrials.gov/ct2/show/NCT04182321. I do not think however it will have a “huge overall positive impact”. A paper l…

Increasing HbsAb and better ultrasound along with increasing Glucose

Just as a follow-up to this study, there has just been this research out showing that in people, there is no lowering of HBsAg achieved by metformin: Randomised controlled trial: effect of metformin add-on therapy on functional cure in entecavir-treated patients with chronic hepatitis B - ScienceDirect Thomas

Thomas