Prioritisation and funding for HBV research - how to help

Thanks @ThomasTu @john.tavis for the overview.
Definitely no scientist here but can appreciate that seems lot of work and maybe politics for that drug to finally get into the hands of people.

How far can advocacy / funding go when there are some many cogs in the wheel?
Where should it be directed on the path?
And that’s without mentioning any government or subsidised costs.